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Case Report
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| Nephrotic syndrome in an adult patient with minimal change disease | ||||||
| Yusuf Alalwan1, Mahmood Alawainati1 | ||||||
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1MB, BCh, BAO, RCSI Bahrain, Kingdom of Bahrain
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| How to cite this article |
| Alalwan Y, Alawainati M. Nephrotic syndrome in an adult patient with minimal change disease. J Case Rep Images Med 2017;3:33–38. |
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Abstract |
| Minimal change disease (MCD) is a glomerulopathy that may manifest as nephrotic syndrome. It is most common in children; while, it only accounts for 20–25% of cases of adult nephrotic syndrome. This article presents a case of an adult with MCD presented with generalized edema. Initially, Focal segmental glomerulosclerosis (FSGS) was suspected. However, the patient’s dramatic response to steroids, his acute presentation and the histopathology features of his renal biopsy favored MCD. The initial management comprised of steroids to which the patient responded. A year later, the patient relapsed and mycophenolate mofetil was added. There is lack of guidelines to manage adult MCD, in contrast to child MCD. The clinical picture of the patient is the key to guide decisions about management in absence of evidence-based guidelines. | |
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Keywords:
Glomerulopathy nephrotic syndrome, Minimal change disease, Steroids, Mycophenolate mofetil
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Acknowledgement
We are thankful to Dr. Ali AlAradi, Consultant Nephrologist, Salmanyia Medical Complex, Bahrain for their help in preparing the manuscript. |
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Author Contributions
Yusuf Alalwan – Substantial contributions conception and design, Acquisition and analysis of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to published Mahmood Alawainati – Substantial contributions conception and design, Acquisition and analysis of data, drafting the article, Revising it critically for important intellectual content, Final approval of the version to published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© 2017 Yusuf Alalwan et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
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